The UK's in/out referendum on membership of the European Union represents a "once-in-a-lifetime decision", Chancellor George Osborne tells the BBC.

The US Episcopal Church is to be barred from key decision-making bodies over its stance on same-sex marriage and homosexuality, Anglican bishops say.

Republican frontrunners Donald Trump and Ted Cruz have begun a televised debate with their party's other White House hopefuls.

A new death from Ebola is confirmed in Sierra Leone, hours after the World Health Organization declared the West Africa outbreak over.

Head teachers condemn England's system for creating new school places, saying it is fragmented and risks harming children's education.

Jakarta's police chief says Indonesia is hunting terror cells in Sulawesi and Java believed to be connected to Thursday's deadly attack in the capital.

Bereaved families have blocked the organ donation of 547 UK registered donors since 2010 - about one in seven cases, figures show.

Pregnant women in the UK should soon get a safer and more accurate test for Down's syndrome, on the NHS, to reduce the risk of miscarriage.